In vitro degradation behavior of chitosan based hybrid microparticles

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In vitro degradation behavior of chitosan based hybrid microparticles.

The degradation properties of the MPs is important to the long-term benefits of the use of the chitosan (CS) based hybrid MPs in bone tissue-engineering, because the degradation kinetics could affect a multitude of processes within the cell, such as cell growth, tissue regeneration, and host response. The aim of this study was to investigate the degradation of solid, hybrid CS microparticles (M...

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Preparation and Characterization of Rivastigmine Transdermal Patch Based on Chitosan Microparticles

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

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ژورنال

عنوان ژورنال: Journal of Biomedical Science and Engineering

سال: 2011

ISSN: 1937-6871,1937-688X

DOI: 10.4236/jbise.2011.45048